Pharmacoepidemiology Post-Doctoral Researcher
Institution:
University of Pennsylvania,
Perelman School of Medicine,
Department of Biostatistics, Epidemiology, and Informatics,
Center for Pharmacoepidemiology Research and Training
Faculty PIs:
Dr. Charles Leonard and
Dr. James Lewis
Description:
About the position:
The postdoctoral researcher will work on two distinct
pharmacoepidemiology-focused studies, each led by a
faculty member in the Division of Epidemiology.
Dr. Leonard, a clinical pharmacist and
pharmacoepidemiologist, is PI of a study entitled “Drug
Interactions Involving Psychoactive Drugs”. This
study will: i) conduct high-throughput automated screening
of longitudinal healthcare data to identify potential drug
interaction pairs and triads leading to unintentional
traumatic injury, including hip fractures and motor
vehicle crashes; ii) convene a multidisciplinary expert
panel to review screening results, prioritize signals for
further investigation, and prespecify hypotheses
buttressed by putative mechanisms; and iii) conduct a
series of rigorous pharmacoepidemiologic studies to inform
causal inferences and thereby generate clinically
actionable evidence on drug interactions to prevent
instances of unintentional traumatic injury.
Dr. Lewis, a gastroenterologist and pharmacoepidemiologist,
is PI of a study entitled “Defining the Incidence,
Prevalence, and Treatment Patterns of Inflammatory Bowel
Disease in the United States”. This study will: i)
build a registry of patients with incident diagnosis of
Crohn’s Disease and ulcerative colitis; ii) estimate the
incidence and prevalence of Crohn’s Disease and ulcerative
colitis at a national level using representative data from
four large claims datasets that encompasses populations
from all segments of the socioeconomic and geographic
distribution of the United States; and iii) determine
whether race and inflammatory bowel disease practice
volume are associated with patterns of care and key
outcomes including use of biologics, steroids, narcotics,
hospitalization and surgery at a national level and within
high volume inflammatory bowel disease centers.
About the University of Pennsylvania:
The University of Pennsylvania’s Perelman School of
Medicine is the oldest medical school in the US. We are
rich in tradition and heritage and at the same time
consistently at the forefront of new developments and
innovations in medical education and research. Since the
medical school’s founding in 1765, we have been a strong
presence in the community and prided ourselves on
educating the leaders of tomorrow in patient care,
biomedical research, and medical education. The Perelman
School of Medicine consistently ranks among the top ten in
US News and World Report’s rankings of research-oriented
medical schools. Our mission is to advance knowledge and
improve health through research, patient care, and the
education of trainees in an inclusive culture that
embraces diversity, fosters innovation, stimulates
critical thinking, supports lifelong learning, and
sustains our legacy of excellence. The Department of
Biostatistics, Epidemiology and Informatics is home to
more than 100 faculty and the graduate education programs
in these three core disciplines. Most faculty are also a
member of the Center for Clinical Epidemiology and
Biostatistics, an interdisciplinary and interdepartmental
program that links clinical epidemiology and biostatistics
within the Perelman School of Medicine, the University of
Pennsylvania Health System, and the Penn community.
Qualifications:
A PhD, ScD, or related doctoral degree in epidemiology,
preferably with a concentration in pharmacoepidemiology
Contact:
Dr. Charles Leonard, 807 Blockley Hall, 423 Guardian
Drive, Philadelphia, PA 19104-4865;
Email:
celeonar@pennmedicine.upenn.edu
Start Date:
02/01/2019 (anticipated, but flexible)
End Date:
As late as 08/31/2023, although appointed in 1-year terms
at the discretion of the PIs
Salary:
Stipend set by the University of Pennsylvania’s Office
of the Vice Provost for Research
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